Dual CCR2/5 Antagonist Attenuates Obesity-Induced Insulin Resistance by Regulating Macrophage Recruitment and M1/M2 Status.

Ji Hye HuhHong Min KimEun Soo LeeMi Hye KwonBo Ra LeeHyun-Jeong KoChoon Hee Chung

Published in: Obesity (Silver Spring, Md.) (2017)

Dual CCR2/CCR5 antagonism ameliorates insulin resistance and inflammation in obesity by regulating ATM recruitment and polarization in white adipose tissue.

Keyphrases

insulin resistance
adipose tissue
high fat diet induced
high fat diet
dendritic cells
regulatory t cells
metabolic syndrome
polycystic ovary syndrome
skeletal muscle
type diabetes
oxidative stress
dna damage
diabetic rats
dna repair
mouse model
dna damage response
drug induced
glycemic control
body mass index