Detection of Pathogenic Bacteria From Septic Patients Using 16S Ribosomal RNA Gene-Targeted Metagenomic Sequencing.
Madiha FidaMatthew J WolfAhmed HamdiPrakhar VijayvargiyaZerelda Esquer GarrigosSarwat KhalilKerryl E Greenwood-QuaintanceMatthew J ThoendelRobin PatelPublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2021)
16S rRNA gene NGS may be useful for detecting bacteria in plasma of septic patients. In some cases of gram-negative sepsis, it may be possible to pinpoint a gastrointestinal or urinary source of sepsis based on the profile of bacteria detected in plasma.