Clinical feasibility and impact of fully automated multiparametric PET imaging using direct Patlak reconstruction: evaluation of 103 dynamic whole-body 18F-FDG PET/CT scans.

D-WB FDG PET/CT is feasible in a clinical setting and produces MRFDG images of good visual quality and superior lesion contrast. In addition, MRFDG images complement the standard SUV images providing better quantification and enhanced image reading. However, although MRFDG also reduced the number of false-positive findings, no additional malignant lesions were identified. The technique therefore appears to be best suited for select patient groups or possibly treatment response evaluation.