A genome-wide association study on low susceptibility to hepatitis C virus infection (GEHEP012 study).
Luis Miguel RealMarta Fernández-FuertesMaría E SáezAntonio RiveroMario FríasFrancisco TéllezJesús SantosDolores MerinoSonia Moreno-GrauJuan Gómez-SalgadoAlejandro González-SernaAnais Corma-GómezAgustín RuizJuan MacíasJuan Antonio PinedaPublished in: Liver international : official journal of the International Association for the Study of the Liver (2019)
Low susceptibility to HCV infection does not seem to be mainly driven by a high-penetrant common allele. By contrast, it seems a multifactorial trait where genes such as LDLR could be involved.