Naturally acquired antibody response to a Plasmodium falciparum chimeric vaccine candidate GMZ2.6c and its components (MSP-3, GLURP, and Pfs48/45) in individuals living in Brazilian malaria-endemic areas.

Barbara Oliveira BaptistaAna Beatriz Lopes de SouzaEvelyn Kety Pratt RiccioCesare Bianco-JuniorPaulo Renato Rivas TotinoJoão Hermínio Martins da SilvaMichael TheisenSusheel Kumar SinghLinda Eva AmoahMarcelo Ribeiro-AlvesRodrigo Medeiros SouzaJosué Costa Lima-JuniorCláudio Tadeu Daniel-RibeiroLilian Rose Pratt-Riccio

Published in: Malaria journal (2022)

The data showed that GMZ2.6c protein is widely recognized by naturally acquired antibodies from individuals living in malaria-endemic areas in Brazil and that these may contribute to parasite immunity. These data highlight the importance of GMZ2.6c as a candidate for an anti-malarial vaccine.

Keyphrases

plasmodium falciparum
electronic health record
big data
cell therapy
binding protein
artificial intelligence
protein protein
small molecule