In a recent study published in Life Metabolism , Quan et al . reported that intracellular Ca 2+ dysregulation in cardiomyocyte can be both a cause and an effect of cardiac insulin resistance that ultimately leads to diabetic cardiomyopathy.
Keyphrases
- insulin resistance
- heart failure
- type diabetes
- adipose tissue
- metabolic syndrome
- high fat diet
- left ventricular
- skeletal muscle
- polycystic ovary syndrome
- high fat diet induced
- protein kinase
- systematic review
- angiotensin ii
- high intensity
- reactive oxygen species
- cardiac resynchronization therapy
- glycemic control
- acute heart failure