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PARPs, PAR and NAD Metabolism and Their Inhibitors in Cancer.

Nicola J CurtinPéter Bai
Published in: Cancers (2020)
The role of poly(ADP-ribose) polymerase-1 (PARP1) in DNA repair and as a potential target for anticancer therapy has been under investigation for more than 50 years [...].
Keyphrases
  • dna repair
  • dna damage
  • papillary thyroid
  • dna damage response
  • squamous cell
  • lymph node metastasis
  • oxidative stress
  • stem cells
  • human health
  • mesenchymal stem cells
  • young adults
  • climate change