Unexpected organellar locations of ESCRT machinery in Giardia intestinalis and complex evolutionary dynamics spanning the transition to parasitism in the lineage Fornicata.

Shweta V Pipaliya Rui Santos Dayana E Salas-Leiva Erina A Balmer Corina D Wirdnam Andrew J Roger Adrian B Hehl Carmen Faso Joel Bryan Dacks

Published in: BMC biology (2021)

Our findings show that ESCRT machinery in G. intestinalis is far more varied and complete than previously thought, associates to multiple cellular locations, and presents changes in ESCRT complement which pre-date adoption of a parasitic lifestyle.

Keyphrases

metabolic syndrome
cardiovascular disease
physical activity
weight loss
single cell
genome wide
dna methylation