Flexible realistic simulation of seizure occurrence recapitulating statistical properties of seizure diaries.

Daniel M Goldenholz Michael Brandon Westover

Published in: Epilepsia (2022)

CHOCOLATES represents the most realistic seizure occurrence simulator to date, based on observations from thousands of patients in different contexts. This tool is open source and flexible, and can be used for many applications, including clinical trial simulation and testing of seizure-forecasting tools.

Keyphrases

clinical trial
temporal lobe epilepsy
end stage renal disease
risk assessment
ejection fraction
chronic kidney disease
virtual reality
prognostic factors
peritoneal dialysis
patient reported outcomes
phase ii