Inferring chromosome radial organization from Hi-C data.

Priyojit DasTongye ShenRachel Patton McCord

Published in: BMC bioinformatics (2020)

Our analysis approaches provide rapid and modular approaches to screen for alterations in CT organization across widely available Hi-C data. We demonstrate which stages of the approach can extract meaningful information, and also describe limitations of pairwise contacts alone to predict absolute 3D positions.

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