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Carfilzomib-induced thrombotic microangiopathy. A case report.

Valentina ScheggiIrene MerilliEdoardo CesaroniBruno Alterini
Published in: Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners (2021)
Drug-induced thrombotic microangiopathy is a rare and often life-threatening acquired condition whose diagnosis can be challenging and whose therapy is not always limited to supportive treatment and drug avoidance. Carfilzomib, along with other proteasome inhibitors, is one of the described potential drugs which can trigger such a manifestation.
Keyphrases
  • drug induced
  • liver injury
  • multiple myeloma
  • adverse drug
  • emergency department
  • risk assessment
  • human health
  • oxidative stress
  • diabetic rats
  • cell therapy
  • climate change
  • smoking cessation