Effect of venlafaxine dosage, valproic acid concentration, sex, and age on steady state dose-corrected concentrations of venlafaxine and O-desmethylvenlafaxine: A retrospective analysis of therapeutic drug monitoring data in a Chinese population.

Zhan-Zhang WangShu-Hua DengHao-Yang LuLu LiXiu-Qing ZhuJin-Qing HuHuan-Shan XieHong-Zhen ChenYu-Qing ChenMing ZhangZi-Yan FangYu-Guan WenDe-Wei Shang

Published in: Human psychopharmacology (2020)

Our results suggested daily dose of VEN, sex, age, and valproic acid as indicators for the C/D of VEN + ODV in Chinese patients. TDM as a valuable tool was suggested in elderly female patients and patients receiving polypharmacy.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
physical activity
emergency department
patient reported outcomes
middle aged
deep learning
artificial intelligence
drug induced