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Fast-Acting Insulin Aspart Improves Glycemic Control in Basal-Bolus Treatment for Type 1 Diabetes: Results of a 26-Week Multicenter, Active-Controlled, Treat-to-Target, Randomized, Parallel-Group Trial (onset 1).

David L Russell-JonesBruce W BodeChristophe De BlockEdward FranekSimon R HellerChantal MathieuAthena Philis-TsimikasLudger RoseVincent C WooAnne Birk ØsterskovTina GraungaardRichard M Bergenstal
Published in: Diabetes care (2017)
Faster aspart effectively improved HbA1c, and noninferiority to IAsp was confirmed, with superior PPG control for mealtime faster aspart versus IAsp. Subjects randomized to postmeal faster aspart for all meals maintained HbA1c noninferior to that obtained with mealtime IAsp.
Keyphrases
  • glycemic control
  • type diabetes
  • double blind
  • phase iii
  • placebo controlled
  • phase ii
  • open label
  • blood glucose
  • clinical trial
  • study protocol
  • insulin resistance
  • weight loss
  • cardiovascular disease
  • metabolic syndrome