Association of cerebrospinal fluid protein biomarkers with outcomes in patients with traumatic and non-traumatic acute brain injury: systematic review of the literature.
Carlos A SantacruzJean-Louis VincentAndres BaderLuis A Rincón-GutiérrezClaudia Dominguez-CurellDavid CommuniFabio S TacconePublished in: Critical care (London, England) (2021)
In patients with acute brain injury, altered CSF concentrations of protein biomarkers related to cytoskeletal damage, inflammation, apoptosis and oxidative stress may be predictive of worse neurological outcomes.
Keyphrases
- brain injury
- oxidative stress
- subarachnoid hemorrhage
- cerebrospinal fluid
- cerebral ischemia
- spinal cord injury
- diabetic rats
- dna damage
- ischemia reperfusion injury
- protein protein
- induced apoptosis
- amino acid
- binding protein
- endoplasmic reticulum stress
- cell death
- drug induced
- type diabetes
- cell cycle arrest
- adipose tissue
- cell proliferation
- metabolic syndrome