Barium chloride injures myofibers through calcium-induced proteolysis with fragmentation of motor nerves and microvessels.

Aaron B MortonCharles E NortonNicole L JacobsenCharmain A FernandoD D W CornelisonSteven S Segal

Published in: Skeletal muscle (2019)

BaCl2 injures myofibers through depolarization of the sarcolemma, causing Ca2+ overload with transient contraction, leading to proteolysis and membrane rupture. Motor innervation and capillarity appear disrupted concomitant with myofiber damage, further compromising muscle integrity.

Keyphrases

high glucose
diabetic rats
oxidative stress
skeletal muscle
drug induced
cerebral ischemia
resting state
endothelial cells
protein kinase
functional connectivity
brain injury
subarachnoid hemorrhage