From metastasis to the primary tumor: Giant liver metastasis from a pancreatic neuroendocrine tumor.
Elena ResinaJosé Carlos García-GilAlejandra Rosell AlayzaAlberto Ezquerra DuránRaquel Muñoz GonzálezLeticia González MorenoMaría CaldasCecilio Santander VaqueroPublished in: Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva (2022)
We present the case of a 37-years old male, who consulted for an extended history of intermittent nausea and vomiting. Laboratory tests showed moderate elevated bilirubin (1.30 mg/dL) and GGT (106 U/L). An abdominal CT scan performed showed a solid 18-centimetres (cm) mass located in the right liver lobe. A biopsy of the lesion was performed, revealing metastastic cells of a well-differentiated neuroendocrine tumour (NET, G3 (Ki-67: 25%). Further study was performed with MRI, and SPECT-CT, showing a 2-cm lesion in the pancreatic tail suggestive of being the primary NET. Chromogranin A levels were high (114.100 ng/ml). In our case, despite the large size of the liver metastasis a full resection of the tumours was achieved.
Keyphrases
- contrast enhanced
- computed tomography
- dual energy
- image quality
- magnetic resonance imaging
- induced apoptosis
- high intensity
- positron emission tomography
- magnetic resonance
- neoadjuvant chemotherapy
- oxidative stress
- diffusion weighted imaging
- radiation therapy
- lymph node
- cell proliferation
- rare case
- fine needle aspiration