Prediction models for the risk of spontaneous preterm birth based on maternal characteristics: a systematic review and independent external validation.

Linda J E MeertensPim van MontfortHubertina C J ScheepersSander M J van KuijkRobert AardenburgJosje LangenveldIvo M A van DoorenIris M ZwaanMarc E A SpaandermanLuc J M Smits

Published in: Acta obstetricia et gynecologica Scandinavica (2018)

This review revealed several reporting and methodological shortcomings of published prediction models for spontaneous preterm birth. Our external validation study indicated that none of the models had the ability to predict spontaneous preterm birth adequately in our population. Further improvement of prediction models, using recent knowledge about both model development and potential risk factors, is necessary to provide an added value in personalized risk assessment of spontaneous preterm birth.

Keyphrases

preterm birth
low birth weight
gestational age
risk assessment
risk factors
birth weight
healthcare
human health
emergency department
systematic review
adverse drug
pregnant women
climate change
pregnancy outcomes
body mass index
drug induced