Evaluation of Cisplatin-Induced Acute Kidney Injury in Patients Co-Prescribed Serotonin Receptor Antagonists: A Retrospective Analysis.

Victoria GutgartsSupriya GerardineRoman A ShingarevAndrea Knezevic Emily C Zabor Sheron LatchaMelanie S JoyLauren M AleksunesEdgar A Jaimes

Published in: Kidney360 (2024)

Nephrotoxicity continues to be a concern following cisplatin therapy. Given its emetogenic nature, use of antiemetic drugs such as 5-HT3RAs can lessen emesis and lower risk of kidney injury. This retrospective analysis supports use of any 5-HT3RAs to lower risk of AKI.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
acute kidney injury
peritoneal dialysis
prognostic factors
stem cells