Growth-regulated oncogene-α from oral submucous fibrosis fibroblasts promotes malignant transformation of oral precancerous cells.

Mei-Yin YeMeng-Yen ChenYa-Han ChangJehn-Shyun HuangTze-Ta HuangTung-Yiu WongTse-Ming HongYuh-Ling Chen

Published in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2018)

GRO-α from OSF-associated fibroblasts paracrinally promotes oral malignant transformation and significantly contributes to OSCC development.

Keyphrases

induced apoptosis
extracellular matrix
oxidative stress
endoplasmic reticulum stress