[ 68 Ga]DOTATOC PET-derived radiomics to predict genetic background of head and neck paragangliomas: a pilot investigation.

Miriam PepponiValentina BertiElsa FasciglioneFlavio MontaniniLetizia CanuFabrice HubeleElisabetta AbenavoliVittorio BrigantiElena RapizziAnne CharpiotDavid TaiebKarel PacakBernard GoichotAlessio Imperiale

Published in: European journal of nuclear medicine and molecular imaging (2024)

Radiomics features GLSZM-ZSNU and IB-TLSRE appear to reflect HNPGLs SDHx status and tumor behavior (metastatic vs. non-metastatic). If validated, especially IB-TLSRE might represent a simple and time-efficient radiomic index for SDHx variants early screening and prediction of tumor behavior in HNPGL cases.

Keyphrases

pet ct
squamous cell carcinoma
small cell lung cancer
lymph node metastasis
copy number
computed tomography
contrast enhanced
genome wide
clinical trial
gene expression
magnetic resonance imaging