Genetic predisposition to central nervous system tumors in children - what the neurosurgeon should know.

Jon Foss-Skiftesvik Ulrik Kristoffer Stoltze

Published in: Acta neurochirurgica (2022)

Germline genetics is becoming increasingly important to clinicians, including neurosurgeons. This review provides an updated overview of genetic predisposition to childhood CNS tumors with focus on aspects relevant to pediatric neurosurgeons.

Keyphrases

genome wide
young adults
copy number
palliative care
blood brain barrier
dna repair
childhood cancer
dna methylation
early life