Single-cell transcriptomics reveals the cell fate transitions of human dopaminergic progenitors derived from hESCs.

Lingmin LiangYao TianLin FengChaoqun WangGuihai FengGlyn Nigel StaceyNg Shyh-ChangJun WuBaoyang HuWei LiJie HaoLiu WangYu-Kai Wang

Published in: Stem cell research & therapy (2022)

Our study provides the single-cell transcriptional landscape of in vitro DA differentiation, which can guide future improvements in DA preparation and quality control for PD cell therapy.

Keyphrases

induced pluripotent stem cells
single cell
cell therapy
quality control
rna seq
cell fate
high throughput
stem cells
mesenchymal stem cells
transcription factor
current status
endothelial cells
high resolution
heat shock
oxidative stress
heat stress