Identification of cyclooxygenase-II inhibitory saponins from fenugreek wastes: Insights from liquid chromatography-tandem mass spectrometry metabolomics, molecular networking, and molecular docking.
Asmaa M KhalilOmar M SabryHesham I El-AskarySoheir M El ZalabaniBasma M EltananyLaura PontFernando BenaventeAhmed ElshewyNesrin M FayekPublished in: Phytochemical analysis : PCA (2024)
In the present study, we focused on the identification of COX-II inhibitory saponins in fenugreek waste through an integrated approach. The findings offer valuable insights into potential anti-inflammatory and cancer chemoprotective applications of fenugreek waste.
Keyphrases
- molecular docking
- liquid chromatography tandem mass spectrometry
- sewage sludge
- simultaneous determination
- anti inflammatory
- heavy metals
- molecular dynamics simulations
- ms ms
- papillary thyroid
- bioinformatics analysis
- solid phase extraction
- mass spectrometry
- municipal solid waste
- squamous cell
- life cycle
- squamous cell carcinoma
- nitric oxide synthase
- risk assessment
- human health
- climate change
- single molecule
- lymph node metastasis
- childhood cancer
- liquid chromatography