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Wounding the stroma: Docetaxel's role in dormant breast cancer escape.

Tyler T CooperLynne-Marie Postovit
Published in: PLoS biology (2023)
The mechanistic underpinnings of breast cancer recurrence following periods of dormancy are largely undetermined. A new study in PLOS Biology reveals that docetaxel-induced injury of tumour stromal cells stimulates the release of cytokines that support dormancy escape of breast cancer cells.
Keyphrases
  • breast cancer cells
  • high glucose
  • locally advanced
  • squamous cell carcinoma
  • endothelial cells
  • oxidative stress
  • breast cancer risk
  • young adults
  • childhood cancer