Wounding the stroma: Docetaxel's role in dormant breast cancer escape.
Tyler T CooperLynne-Marie PostovitPublished in: PLoS biology (2023)
The mechanistic underpinnings of breast cancer recurrence following periods of dormancy are largely undetermined. A new study in PLOS Biology reveals that docetaxel-induced injury of tumour stromal cells stimulates the release of cytokines that support dormancy escape of breast cancer cells.