The quantitative analysis of the human papillomavirus DNA load in submandibular gland lesions with droplet digital polymerase chain reaction.

Ryuhei OkadaTaku ItoFuminori NomuraSusumu KirimuraYuichiro ChoMasaki SekineYumiko TateishiYosuke AriizumiTakahiro Asakage

Published in: Acta oto-laryngologica (2019)

HPV-DNA positivity and p16INK4A-immunoreactivity were not correlated in submandibular gland lesions. The loads of HPV DNA detected in this study were small. HPV positivity therefore may not be associated with tumorigenesis of the submandibular gland.

Keyphrases

circulating tumor
cell free
high grade
single molecule
high throughput
circulating tumor cells
single cell
real time pcr