IDH1 mutation activates mTOR signaling pathway, promotes cell proliferation and invasion in glioma cells.
Timucin AvşarTansu Bilge KoseMuhammed Deniz OksalGizem TuranTurker KilicPublished in: Molecular biology reports (2022)
Our results highlighted IDH1 mutation upregulate mTOR signaling pathway and promote cell proliferation, invasion and migration.