Efficacy and safety of etrasimod, a sphingosine 1-phosphate receptor modulator, in adults with moderate-to-severe atopic dermatitis (ADVISE).
Jonathan Ian SilverbergRobert BissonnetteLeon KircikDedee F MurrellAndrew SelfridgeKris LiuGurpreet AhluwaliaEmma Guttman-YasskyPublished in: Journal of the European Academy of Dermatology and Venereology : JEADV (2023)
The primary outcome was not met, though efficacy was observed for etrasimod 2 mg on several clinician- and patient-assessed measures, and both 1-mg and 2-mg doses were well tolerated, warranting further clinical investigation in AD.