FAM3C in Cancer-Associated Adipocytes Promotes Breast Cancer Cell Survival and Metastasis.

Sahee Kim Jiyoung Oh Chanho Park Min Kim Woobeen Jo Chu-Sook Kim Sun Wook Cho Jiyoung Park

Published in: Cancer research (2024)

High FAM3C levels in cancer-associated adipocytes contribute to tumor-supportive niches and are tightly associated with metastatic growth, indicating that FAM3C inhibition could be beneficial for treating patients with breast cancer.

Keyphrases

adipose tissue
squamous cell carcinoma
small cell lung cancer
high fat diet induced
type diabetes
insulin resistance
metabolic syndrome