Airway and parenchyma immune cells in influenza A(H1N1)pdm09 viral and non-viral diffuse alveolar damage.
Monique ButtignolRuy Camargo Pires-NetoRenata Calciolari Rossi E SilvaMarina Ballarin AlbinoMarisa DolhnikoffThais MauadPublished in: Respiratory research (2017)
DAD due to viral A(H1N1)pdm09 is associated with a cytotoxic inflammatory phenotype, with partially divergent responses in the parenchyma relative to the small airways. In non-viral DAD, main immune cell alterations were found at the small airway level, reinforcing the role of the small airways in the pathogenesis of the exudative phase of DAD.