Rationale for and Design of the Study of Early Enteral Dextrose in Sepsis: A Pilot Placebo-Controlled Randomized Clinical Trial.
Faraaz Ali ShahGeorgios D KitsiosYingze ZhangAlison MorrisSachin YendeDavid T HuangChristopher P O'DonnellBryan J McVerryPublished in: JPEN. Journal of parenteral and enteral nutrition (2019)
This trial will characterize the effects of early enteral dextrose on endogenous endocrine pathways and the systemic inflammatory response in sepsis. The results of this trial will inform future larger interventional studies of early enteral nutrients in critically ill patients with sepsis.
Keyphrases
- study protocol
- inflammatory response
- acute kidney injury
- intensive care unit
- septic shock
- phase iii
- clinical trial
- phase ii
- placebo controlled
- double blind
- randomized controlled trial
- immune response
- lipopolysaccharide induced
- heavy metals
- toll like receptor
- squamous cell carcinoma
- risk assessment
- radiation therapy
- lps induced
- phase ii study