p16, p21, and p53 proteins play an important role in development of pancreatic intraepithelial neoplastic.
Justyna DorfKonrad ZarębaKatarzyna Guzińska-UstymowiczBogusław KędraAndrzej KemonaAnna PryczyniczPublished in: Irish journal of medical science (2018)
p16, p21, and p53 proteins play an important role in the deregulation of the cell cycle and participate in the development of pancreatic intraepithelial neoplasia. Immunohistochemical evaluation of their expressions may be helpful in the diagnosis of PanIN.
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