Anesthetic-loaded nanodroplets with focused ultrasound reduces agitation in Alzheimer's mice.

Flavia Venetucci GouveiaHarriet Lea-BanksIsabelle AubertNir LipsmanKullervo HynynenClement Hamani

Published in: Annals of clinical and translational neurology (2023)

Our results show that neuromodulation with active-nanoFUS may be a potential therapeutic tool for the treatment of neuropsychiatric symptoms, with special focus on agitation and aggressive behaviors. Further studies are necessary to establish cellular, molecular and long-term behavioral changes following treatment with nanoFUS.

Keyphrases

drug delivery
combination therapy
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metabolic syndrome
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insulin resistance
high fat diet induced
case control
wound healing