Delta power robustly predicts cognitive function in Angelman syndrome.
Lauren M OstrowskiElizabeth R SpencerLynne M BirdRonald ThibertRobert W KomorowskiMark A KramerCatherine J ChuPublished in: Annals of clinical and translational neurology (2021)
Delta power is a simple, direct measure of neuronal activity that reliably correlates with cognitive function in AS. This electrophysiological biomarker offers an objective, clinically relevant endpoint for treatment response in emerging clinical trials.