Near-infrared dye-labeled antibody COC183B2 enables detection of tiny metastatic ovarian cancer and optimizes fluorescence-guided surgery.

Junchen ChenYanxiu GuoHui LiChen ZhangXiaohong ChangRuiqiong MaHongyan ChengXue YeHeng CuiYi Li

Published in: Journal of surgical oncology (2020)

COC183B2-Cy7 probe has relatively high specificity and sensitivity. Our study suggests that COC183B2-Cy7 probe is a promising diagnostic tool for the complete and accurate resection of malignant lesions in fluorescence-guided surgery.

Keyphrases

minimally invasive
coronary artery bypass
single molecule
living cells
squamous cell carcinoma
small cell lung cancer
quantum dots
surgical site infection
energy transfer
high resolution
highly efficient
pet imaging
fluorescent probe
label free
structural basis