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Congenital aqueduct stenosis: Progressive brain findings in utero to birth in the presence of severe hydrocephalus.

Julia E KlineMonica S ArroyoMaria A Calvo-GarciaPaul S HornCameron Thomas
Published in: Prenatal diagnosis (2018)
Hydrocephalus in the fetus results in enlarging ventricular rupture, loss of the septum pellucidum leaflets, volume reduction of brain parenchyma including corpus callosum, and risk for Chiari I anomaly. Given advances in fetal surgery and imaging in the last 3 decades, there may be cause to revisit the idea of in utero cerebral spinal fluid diversion as a means to potentially ameliorate progressive loss of the developing brain.
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