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Role of offset and gradient architectures of 3-D melt electrowritten scaffold on differentiation and mineralization of osteoblasts.

Naghmeh AbbasiSaso IvanovskiKaran GulatiRobert M LoveStephen M Hamlet
Published in: Biomaterials research (2020)
This study demonstrated that the heterogenous pore sizes in gradient and fibre offset PCL scaffolds prepared using MEW significantly improved the osteogenic potential of osteoblasts and hence may provide superior outcomes in bone regeneration applications.
Keyphrases
  • bone regeneration
  • tissue engineering
  • mesenchymal stem cells
  • type diabetes
  • metabolic syndrome
  • insulin resistance
  • weight loss
  • glycemic control