Our data demonstrated that HOTAIRM1 knockdown could inhibit apoptosis and oxidative stress and activated the Nrf2/HO-1 pathway, therefore exerting neuroprotective effect on the PD cell model.
Keyphrases
- oxidative stress
- induced apoptosis
- cell cycle arrest
- pi k akt
- signaling pathway
- diabetic rats
- endoplasmic reticulum stress
- ischemia reperfusion injury
- dna damage
- single cell
- cell death
- electronic health record
- cell therapy
- hydrogen peroxide
- stem cells
- machine learning
- big data
- mesenchymal stem cells
- cell proliferation
- heat shock
- artificial intelligence