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Metastatic olfactory neuroblastoma: A small round blue cell puzzle on fine-needle aspiration cytology.

Ingrid H PenzhornPawel Tomasz Schubert
Published in: Diagnostic cytopathology (2021)
Small round blue cell tumors (SRBCTs) are a heterogeneous group of malignant neoplasms that can be challenging to distinguish on fine-needle aspiration (FNA) cytology. Ancillary tests as well as clinico-radiological correlation are often required to make an accurate diagnosis. FNA is a low-cost, low-infrastructure test, making it a coveted diagnostic tool, especially in low-resource settings. Olfactory neuroblastoma (ONB) is a rare SRBCT encountered in both pediatric and adult patients. Awareness of the cytomorphologic and immunocytochemical features of ONB is important in the workup of a SRBCT. This case report describes the primary diagnosis of metastatic ONB on FNA cytology.
Keyphrases
  • fine needle aspiration
  • ultrasound guided
  • low cost
  • case report
  • small cell lung cancer
  • squamous cell carcinoma
  • single cell
  • cell therapy
  • high resolution
  • mass spectrometry