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CpG Oligodeoxynucleotides Inhibit RANKL-Induced Osteoclast Formation by Upregulating A20 Deubiquitinase in RAW 264.7 Cells.

Seong Kyu KimJung-Yoon ChoeKi Yeun Park
Published in: Mediators of inflammation (2022)
This study showed that CpG-ODN suppressed RANKL-induced osteoclast formation through regulation of the A20-TRAF6 axis in RAW 264.7 cells.
Keyphrases
  • induced apoptosis
  • bone loss
  • cell cycle arrest
  • high glucose
  • dna methylation
  • endoplasmic reticulum stress
  • signaling pathway
  • oxidative stress
  • immune response
  • cell proliferation
  • endothelial cells
  • toll like receptor