Loss of Uncoupling Protein 3 Attenuates Western Diet-Induced Obesity, Systemic Inflammation, and Insulin Resistance in Rats.

Tyler M LomaxSadia AshrafGizem YilmazRomain Harmancey

Published in: Obesity (Silver Spring, Md.) (2020)

Loss of UCP3 partially protects rats from diet-induced obesity. This phenotype is related to induction of a compensatory antioxidant mechanism and prevention of iBAT whitening.

Keyphrases

insulin resistance
metabolic syndrome
weight loss
high fat diet induced
type diabetes
weight gain
oxidative stress
anti inflammatory
small molecule
nitric oxide synthase