Acute Pontine Ischemic Stroke in a Healthy Child With Intracranial Vasculopathy.
Youssef A KousaJonathan MurnickJustin BurtonMarc DiSabellaPaola PergamiPublished in: Journal of child neurology (2019)
Here we report the case of a previously healthy 8-year-old boy who presented with altered mental status, right facial droop and right-sided hemiplegia the day after playing in an inflatable bouncer. No head trauma was reported by the patient nor witnessed by the parents. Urgent magnetic resonance imaging (MRI) demonstrated acute ischemic infarction in the left pons; computed tomographic angiography excluded arterial dissection but identified a small hyperdense filling defect in the basilar artery, later confirmed to be a calcification at the origin of a perforating artery. Pediatric National Institutes of Health (PedNIH) Stroke Scale score was 15. Infectious, inflammatory, hypercoagulable and additional vascular causes were excluded. Although the cause of the calcification remains obscure, we speculate that, similarly to mineralizing microangiopathy, a minor trauma led to stroke in this child. To our knowledge, mineralizing microangiopathy, the well-described entity affecting perforating arteries of the anterior circulation in young children leading to basal ganglia stroke following minor head traumas has not been described in the posterior circulation or in previously healthy school-age children.
Keyphrases
- atrial fibrillation
- magnetic resonance imaging
- mental health
- liver failure
- healthcare
- optic nerve
- respiratory failure
- computed tomography
- optical coherence tomography
- cerebral ischemia
- contrast enhanced
- public health
- drug induced
- aortic dissection
- young adults
- oxidative stress
- quality improvement
- ischemia reperfusion injury
- health information
- case report
- intensive care unit
- subarachnoid hemorrhage
- hepatitis b virus
- blood flow
- brain injury
- mechanical ventilation
- extracorporeal membrane oxygenation
- climate change
- childhood cancer