Da Cheng Qi Decoction Alleviates Cerulein-Stimulated AR42J Pancreatic Acinar Cell Injury via the JAK2/STAT3 Signaling Pathway.

Zehua Zhou Ying Chen Wenmin Dong Rui An Kun Liang Xinhong Wang

Published in: Evidence-based complementary and alternative medicine : eCAM (2021)

The activation of JAK2/STAT3 pathway may play a key role in the pathogenesis of cerulein-stimulated AR42J pancreatic acinar cell injury. DCQD could improve inflammatory cytokines and cell injury, which might be mediated by suppressing the activation of JAK2/STAT3 signaling pathway.

Keyphrases

signaling pathway
single cell
cell therapy
pi k akt
stem cells
mouse model
oxidative stress
cell proliferation