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Agonistic properties of a series of psychotropic drugs at 5-HT 1A receptors in rat and human brain membranes determined by [ 35 S]GTPγS binding assay.

Yuji OdagakiMasaki MikamiMasakazu KinoshitaJosé Javier MeanaLuis F CalladoJesús A García-SevillaDasiel Oscar Borroto-EscuelaKjell Fuxe
Published in: Pharmacological reports : PR (2023)
receptor agonism, consisting of perospirone, aripiprazole, ziprasidone, clozapine, quetiapine, nemonapride, and trazodone. The present study demonstrates the data indicating that brexpiprazole and probably vortioxetine are included in this drug group. Lurasidone and asenapine are excluded from this group.
Keyphrases
  • major depressive disorder
  • oxidative stress
  • electronic health record
  • high throughput
  • bipolar disorder
  • emergency department
  • big data
  • dna binding
  • adverse drug
  • data analysis
  • artificial intelligence