Apigetrin alleviates intervertebral disk degeneration by regulating nucleus pulposus cell autophagy.

Tao XuHongqi ZhaoJian LiXuan FangHua WuWei-Hua Hu

Published in: JOR spine (2024)

API inhibited degenerative phenotypes and promoted autophagy in vivo and in vitro IVDD models. Those suggested that API might be a potential drug or target for IVDD.

Keyphrases

cell death
endoplasmic reticulum stress
signaling pathway
oxidative stress
single cell
cell therapy
mouse model
stem cells
risk assessment
bone marrow
electronic health record