Anticancer Potential of Resveratrol, β-Lapachone and Their Analogues.

Danielly C Ferraz da CostaLuciana Pereira RangelMafalda Maria Duarte da Cunha Martins-DinisGiulia Diniz da Silva FerrettiVitor F FerreiraJerson Lima Silva

Published in: Molecules (Basel, Switzerland) (2020)

This review aims to explore the potential of resveratrol, a polyphenol stilbene, and beta-lapachone, a naphthoquinone, as well as their derivatives, in the development of new drug candidates for cancer. A brief history of these compounds is reviewed along with their potential effects and mechanisms of action and the most recent attempts to improve their bioavailability and potency against different types of cancer.

Keyphrases

papillary thyroid
squamous cell
human health
emergency department
lymph node metastasis
molecular docking
adverse drug