LIM-Nebulette Reinforces Podocyte Structural Integrity by Linking Actin and Vimentin Filaments.

Xu-Hua Ge Tao ZhangXiaoxia YuAlecia N MuwongeNanditha Anandakrishnan Nicholas J Wong Jonathan C HaydakJordan M ReidJia FuJenny S WongSmiti BhattacharyaChristina M CuttittaFang ZhongRonald E GordonFadi E SalemWilliam JanssenJames C HoneAihua ZhangHong LiJohn C HeG Luca GusellaKirk N CampbellEvren U Azeloglu

Published in: Journal of the American Society of Nephrology : JASN (2020)

LIM-nebulette is a multifunctional cytoskeletal protein that is critical in the maintenance of podocyte structural integrity through active reorganization of focal adhesions, the actin cytoskeleton, and intermediate filaments.

Keyphrases

diabetic nephropathy
high glucose
cell migration
drug delivery
cancer therapy
protein protein
binding protein
small molecule