An imbalance of netrin-1 and DCC during nigral degeneration in experimental models and patients with Parkinson's disease.

Ye HuaWenjing HanLinfeng ZhouJing GaoJifeng ZhaoNanshan SongBin HuQingyu YaoYumin LiuDeen XuYunnan LuYi Fan

Published in: CNS neuroscience & therapeutics (2023)

Our findings confirmed the imbalance of NTN-1/DCC signaling during nigral degeneration in experimental PD models and found for the first time a correlation of plasma NTN-1 with PD symptoms in patients.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
patient reported outcomes
sleep quality