Multiethnic PDX models predict a possible immune signature associated with TNBC of African ancestry.
Evelyn M JiaggePeter J UlintzShukmei WongSean P McDermottSabrina I FossiTahra K SuhanMark J HoenerhoffJessica M BensenhaverBarbara SalemMichele DziubinskiJoseph K OppongFrancis AitpillahKyei IshmaelErnest Osei-BonsuErnest AdjeiAwuah BaffourJessica AldrichAhmet KurdogluKurt FernandoDavid W CraigJeff M TrentJun LiDhananjay ChitaleLisa A NewmanJohn D CarptenMax S WichaSofia D MerajverPublished in: Breast cancer research and treatment (2021)
Further exploration of the role of immune regulated genes and biological processes in BCSC may offer insight into developing novel approaches to treating TNBC to help ameliorate survival disparities in women with African ancestry.