Sacubitril/valsartan in real-life European patients with heart failure and reduced ejection fraction: a systematic review and meta-analysis.
Stefano GiovinazzoLuca CarmiscianoMatteo TomaStefano BenenatiDaniela TomasoniMaria Pia SormaniItalo PortoMarco CanepaMichele SenniMarco MetraPietro AmeriPublished in: ESC heart failure (2021)
Limited-quality RWE indicates that there are important differences between European patients prescribed sacubitril-valsartan and the PARADIGM-HF population, including the frequency of target dose achievement.