Comparison of medium to long-term outcomes of acute severe ulcerative colitis patients receiving accelerated and standard infliximab induction.

David J GibsonJayne DohertyMairead McNallyJohn CampionDenise KeeganAine KeoghUna KennedyKathryn ByrneLaurence J EganSusan McKiernanFInbar MacCarthySubhasish SenguptaJuliette SheridanHugh E MulcahyGarret CullenEoin SlatteryDavid KevansGlen A Doherty

Published in: Frontline gastroenterology (2019)

Time to colectomy is significantly prolonged with use of AD IFX in selected ASUC patients with more severe disease. Historical use of standard IFX induction for all ASUC patients is associated with inferior long-term outcomes.

Keyphrases

ulcerative colitis
end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
early onset
drug induced
liver failure
prognostic factors
peritoneal dialysis
patient reported outcomes
intensive care unit
hepatitis b virus
aortic dissection
patient reported
clinical evaluation